Protease Inhibitors and Phosphatase Inhibitors
MilliporeSigma™ Calbiochem™ PPACK II, Trifluoroacetate Salt
Potent and specific irreversible inhibitor of plasma and glandular kallikreins.
MilliporeSigma™ Calbiochem™ Camptothecin, 10-Hydroxy-, Camptotheca acuminata
A cell-permeable powerful DNA topoisomerase I inhibitor.
MilliporeSigma™ Calbiochem™ TRPV4 Agonist, GSK1016790A
A cell-permeable, potent, selective agonist of TRPV4 channel. Enhances Ca2+ flux in a variety of human and mouse cells (EC50 = 2.1 nM for human TRPV4).
MilliporeSigma™ Calbiochem™ StemSelect™ PD 0332991
A cell-permeable, brain permeant, potent, reversible, ATP competitive inhibitor of Cdk4 and Cdk6 (IC50 = 11, 9, and 15 nM for Cdk4/D1, Cdk4/D3 and Cdk6/D2, respectively).
MilliporeSigma™ Calbiochem™ Pterostilbene, Pterocarpus marsupium
A cell-permeable methoxylated analog of Resveratrol that displays antioxidant, antiproliferative, and hypoglycemic properties.
MilliporeSigma™ Calbiochem™ HIF Inhibitor VI
The HIF-1 Inhibitor, NSC-134754 controls the biological activity of HIF-1. This small molecule/inhibitor is primarily used for Cell Structure applications.
MilliporeSigma™ Calbiochem™ Indomethacin
A non-steroidal anti-inflammatory, cell permeable, antipyretic agent.
MilliporeSigma™ Calbiochem™ Caspase-3/7 Inhibitor II
The Caspase-3/7 Inhibitor II, also referenced under CAS 775289-20-8, controls the biological activity of Caspase-3/7. This small molecule/inhibitor is primarily used for Cancer applications.
MilliporeSigma™ Calbiochem™ Adenosine Deaminase Inhibitor, DCF
The Adenosine Deaminase Inhibitor, DCF, also referenced under CAS 53910-25-1, controls the biological activity of Adenosine Deaminase.
MilliporeSigma™ Calbiochem™ Celastrol, Celastrus scandens
A cell-permeable dienone-phenolic triterpene compound that exhibits antioxidant and anti-inflammatory properties.
MilliporeSigma™ Calbiochem™ Cathepsin B Inhibitor II
The Cathepsin B Inhibitor II controls the biological activity of Cathepsin B. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
MilliporeSigma™ Calbiochem™ Cathepsin L Inhibitor, CAA0225
An epoxysuccinyl peptide highly selective for rat liver cathepsin L (IC50
MilliporeSigma™ Calbiochem™ ISR Inhibitor, ISRIB
The cell-permeable, selective inhibitor of eIF2α/eIF2S1 Ser51 phosphorylation-initiated UPR response (≈25 to 200 nM) upon ER stress induction.
MilliporeSigma™ Calbiochem™ SKF-97541
A highly potent agonist of GABAB receptor. Shown to be about 10-times more potent than baclofen.
MilliporeSigma™ Calbiochem™ Adenosine A1 Receptor Agonist I, CPA
A potent and selective agonist of adenosine A1 receptor (A1R) (Ki